Colts vs 49ers live updates: TV info, picks, how to watch Week 16 Monday Night Football
- Posted on December 22, 2025
- By Usa Today
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Colts vs 49ers live updates: TV info, picks, how to watch Week 16 Monday Night Football
Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's TV channel, odds and more for Week 16.
