Researchers decipher structure of a human protease implicated in various diseases

Modifications in proteins after they are synthesized (post-translational) are changes that play a fundamental role in cell regulation, as they can alter biological activity and influence various physiological processes. There are many types, including SUMOylation, a mechanism in which the SUMO (Small Ubiquitin-like MOdifier) protein binds to other proteins and modulates their functions.